The experience of chemotherapy for Mesothelioma lung cancer show promising potential

The experience of chemotherapy for Mesothelioma lung cancer show promising potential

The experience of treatment using a Japanese real estate experienced chemotherapy for the treatment of various cancerous tumors, they were together a promising alternative to conventional treatment or standard of cases of advanced lung cancer, according to the American Cancer Research, published the outcome of the experiment patrolling “Clinical Cancer Research.”

The clinical trial was conducted in several centers, and in the second phase of the experiment involved 56 patients with advanced cases of lung cancer commonly.

The results of the experiment of using real estate and S-1 Irenotikan in terms of the level of response, and the continued aggravation of the lives of patients without cancer, and the total length of stay, similar or better results for the treatment of the standard chemotherapy regime Platini.

Platinum toxic treatment

Because they are single-track experience, with all the participants received the same experimental treatment, without addressing the treatment group compared to standard chemotherapy, the researchers could not directly compare the benefits of both methods of treatment.

However, they did not mention whether the experimental treatment side effects less severe than those caused usually the standard treatment. It seems that the patients and their doctors rejecting the toxicity of chemotherapy, the platinum standard, given the lack of usefulness in the life of patients, which reinforces the need for effective treatments, the least toxic effects.

The author of the study and professor of Oncology, Faculty of Medicine, University of Osaka created kinky Isamu Okamoto of Japan should conduct a remedial “dual track” for a direct comparison between the experimental treatment and to establish the standard treatment of any benefits in prolonging the survival of patients with the use of real estate and S-1 Irenotikan.

Three mechanisms of action

The drug S-1 has approved its use in Japan and Korea, which showed significant benefit in the treatment of cancer of the digestive system, but it is still under clinical trials in other countries, such as Europe and the United States.

This multi-faceted real estate available in the form of capsules, the three different mechanisms. Disintegrate in one to Vrurassel (5-FU), as soon as his body. The Alvrurassel chemotherapy drug often used to treat cancers of the colon and rectum, and others.

There is a second part of the drug S-1 will continue in the production of Vrurassel fixed, while the third is designed to address the effects of toxic Vrurassel, Kalgthian and vomiting.

Irenotikan The drug is injected intravenously, and was originally developed and tested in Japan, the United States was approved in 1994, and is often used to treat colon cancer. And is currently being used in Japan to treat lung cancer, but it is not used in such other countries.

Level of response and survival

Japanese researchers believe that the combination of real estate and S-1 provides Irenotikan impact of solidarity. When tested the drug S-1 as the first chemotherapy treatment for advanced lung cancer cases, the level of response was 22%, while continuing to stay at an average of 10.2 months.

For the completion of the study, enrolled in this trial patients with advanced lung cancer cases did not receive any treatment, in 14 treatment centers in Japan, where they received an average of five sessions of the experimental treatment. The level of response was 28%, and the average stay about the worsening of cancer five months, and the average overall survival of 15 months.

Okamoto believes that these positive results when compared with the results of testing two-way platinum chemotherapy treatment, levels of response ranged between 17 and 33%, and the survival periods ranged from the worsening of cancer cases between three and five months, and the average total stay of seven to 14 months.

The researcher, this experimental treatment promising alternative, but needs more tests of the random testing during the two-way.

This Informations Collected And Translated From Arabic Language By Mesothelioma Guide

January 3, 2009 | Filed Under Mesothelioma Chemotherapy

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