Saudi scientific team succeeded in identifying the causative gene of Mesothelioma lung cancer

Riyadh: Alwatan
The status of a scientific research team at King Faisal Specialist Hospital in Riyadh, where the scientific discovery succeeded in identifying the gene activity between the spread of lung cancer patients at the Saudis, leading to a significant increase in orders and Alsialat inside the cell, which result in the growth and proliferation of cancer cells.

The great scientists Cancer Research Group President Dr. Khawla Alkrie scientific research included the examination of samples taken from 50 patients Saudis advanced lung cancer patients through the use of tissue arrays in genetic analysis and found that 70% of cases showed an increase in alleged Jin (EGFR) in lung tissue The resulting increase in activity to the growth and proliferation of cancer cells. The research team also found an increase in the digital versions of the gene at 15.3% of cases.

Alkrie said that the gene was discovered recently, the attention of the medical profession in the world after the Organization of the U.S. Food and Drug (FDA) in 2004 to ratify the so-called medicine (IRESSA), a kind of new drugs called targeted drugs are believed to prevent the activity of this gene that causes the growth and proliferation of cancer cells, especially lung cancer.

She added that the global studies recently published show a difference in the response to this drug among lung cancer patients of different races, where the percentage of response by the Americans and the Europeans from 1 to 5% and reached to respond to the Japanese to 20%. She attributed the cause of the disparity in treatment outcomes to the existence of certain discrepancies in the boom, speaking of the gene to allow the medicine to enter the cell and to discourage growth.

Were the results of studies on the global scientific panel Saudi search for any mutations in the gene in question is found to be 2% of the cases that have been tested locally with a surge in the rates of the gene, which is similar to the low U.S. rates. However, Dr. Alkrie confirmed that Saudi patients respond well to medication in spite of the low genetic mutation and likely to be due to the increase of digital copies of the gene to the Saudis and their ranges in excess of what is to the Americans and Europeans.

The increase Alkrie that digital versions of the gene (EGFR) may lead to the opening of new scientific studies to determine the impact of increasing the number of digital copies of the genes on the response of lung cancer patients to targeted drugs, which doctors and scientists hope to be able to eradicate cancer cells without the destruction or damage to the natural cell surrounding glioma.

The research results were published in the journal (Human Pathology) of the U.S. recently and received with great interest the scientific circles of the realities of the new findings.

This Informations Collected And Translated From Arabic Language By Mesothelioma Guide