Disclosure of important steps for the treatment of Mesothelioma lung cancer
Disclosure of important steps for the treatment of Mesothelioma lung cancer
Tamer Abul Enein - Geneva
Revealed the first European Conference of lung tumors in Geneva on new research in the field of diagnosis and treatment of lung cancer at an early date and the prospects for the prevention of the emergence of tumors after treatment.
The inauguration of this conference, which took place in the period between 24 and 27 April
A database for the exchange of information on the latest developments in research and treatment of this pernicious disease.
Three genes
The Italian researchers reported in a scientific paper to the conference, that the genetic analysis could help in identifying patients at risk of a major setback after the surgery, the removal of tumors of the lung.
The president of the research, Professor Guido Natoli from Italy, “The track mark of three specific genes that could help in the tumors of lung specialists to choose the best treatment after surgery, to ensure that the spread of cancer cells again.”
Strengthen the immune
On the other hand, discussed the conference - which is the first fruit of cooperation between the European Society for Medical Oncology and the International Association for the study of lung cancer - research on the impact of gene therapy using anti-cancer cells.
Said Professor Johan Vannsteinkest from Belgium, “The results of this method to relieve the patient’s exposure to any side effects when used self chemotherapy after removal of tumors of the lung.”
This method relies on the patient during the injection of certain doses of a substance specific MAGE-A3 ASCI Vannsteinkest asserts that it was working to strengthen the immune system cells in the lung.
Database
During this conference inaugurated the database could be open to the Internet, including information on the results and steps to treat 12244 patients, specialists will be exposed through the development of specific types of treatment, and how the patient’s response to them and under what circumstances.
According to the statistics of the World Health Organization, the number of people living with lung cancer each year up to 1.3 million people 90% of them are smokers.
The proportion of deaths due to lung cancer, approximately 12.5% of deaths annually in the world, which is equivalent to 11 million people.
Source: aljazeera
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This Informations Collected And Translated From Arabic Language By Mesothelioma Guide
A new drug for the most common types of Mesothelioma lung cancers
The scientists tested a new drug to determine the extent of its ability to initial treatment for the most common types of lung cancers.
And know the name of the new drug Tarceva, which is produced by Roche and Genntek Osei, was finally adopted in the United States.
June British scientists at the Center for Research on Cancer and the University of London University Kdig to try the drug on 664 patients with advanced lung cancer cells, a type of non-small can be treated by conventional means.
Researchers say the President, Dr. Siu Meng Li conventional chemotherapy did not help very much in the treatment of advanced lung cancer cells that neoplasms quickly become resistant to treatment, while chemotherapy does not distinguish adequately between the cells Almtsrtunp and other sound effects in addition to the side difficult for patients with lung cancer that Ikavhoha successfully.
Tarceva is one of the new cancer drugs known as medicines, “smart” as the pill only in the day that used to impede the movement of the patient molecule known as “the future of the human growth factor”, which convey the orders to the cells to grow and make it fall.
The scientists in addition to monitoring the evolution of the situation analysis of patient tumors and determine the quality and the proportion of the molecule in the body to determine the extent of the patient’s response to the drug in question.
Meng Li says, “The testing of such a large-scale will play a decisive role in the evaluation of the new smart cancer drugs and to have access to the most effective types and distribution to the clinics as soon as possible.”
States that lung cancer is the most common cancer in the world, affecting 900 thousand men and 330 thousand women in the world each year, according to the international body of research in the field of cancer.
The proportion of cases of lung cancer than non-small cell to 75% of all cases of lung cancer, and return to the diagnosis of the disease are often in the later stages.
The other hand, will test the drug in 100 health centers in Britain, where patients will be selected at random and given some of Tarceva, while giving others a similar bogus pills in addition to radiotherapy, if found necessary, as the scientists hope to complete those tests within a year from now.
Meng Li says, “If the drug proved successful, it will be an ideal treatment.”
Source: Reuters
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The experience of chemotherapy for lung cancer show promising potential
Mazen Al Najjar
The experience of treatment using a Japanese real estate experienced chemotherapy for the treatment of various cancerous tumors, they were together a promising alternative to conventional treatment or standard of cases of advanced lung cancer, according to the American Cancer Research, published the outcome of the experiment patrolling “Clinical Cancer Research.”
The clinical trial was conducted in several centers, and in the second phase of the experiment involved 56 patients with advanced cases of lung cancer commonly.
The results of the experiment of using real estate and S-1 Irenotikan in terms of the level of response, and the continued aggravation of the lives of patients without cancer, and the total length of stay, similar or better results for the treatment of the standard chemotherapy regime Platini.
Platinum toxic treatment
Because they are single-track experience, with all the participants received the same experimental treatment, without addressing the treatment group compared to standard chemotherapy, the researchers could not directly compare the benefits of both methods of treatment.
However, they did not mention whether the experimental treatment side effects less severe than those caused usually the standard treatment. It seems that the patients and their doctors rejecting the toxicity of chemotherapy, the platinum standard, given the lack of usefulness in the life of patients, which reinforces the need for effective treatments, the least toxic effects.
The author of the study and professor of Oncology, Faculty of Medicine, University of Osaka created kinky Isamu Okamoto of Japan should conduct a remedial “dual track” for a direct comparison between the experimental treatment and to establish the standard treatment of any benefits in prolonging the survival of patients with the use of real estate and S-1 Irenotikan.
Three mechanisms of action
The drug S-1 has approved its use in Japan and Korea, which showed significant benefit in the treatment of cancer of the digestive system, but it is still under clinical trials in other countries, such as Europe and the United States.
This multi-faceted real estate available in the form of capsules, the three different mechanisms. Disintegrate in one to Vrurassel (5-FU), as soon as his body. The Alvrurassel chemotherapy drug often used to treat cancers of the colon and rectum, and others.
There is a second part of the drug S-1 will continue in the production of Vrurassel fixed, while the third is designed to address the effects of toxic Vrurassel, Kalgthian and vomiting.
Irenotikan The drug is injected intravenously, and was originally developed and tested in Japan, the United States was approved in 1994, and is often used to treat colon cancer. And is currently being used in Japan to treat lung cancer, but it is not used in such other countries.
Level of response and survival
Japanese researchers believe that the combination of real estate and S-1 provides Irenotikan impact of solidarity. When tested the drug S-1 as the first chemotherapy treatment for advanced lung cancer cases, the level of response was 22%, while continuing to stay at an average of 10.2 months.
For the completion of the study, enrolled in this trial patients with advanced lung cancer cases did not receive any treatment, in 14 treatment centers in Japan, where they received an average of five sessions of the experimental treatment. The level of response was 28%, and the average stay about the worsening of cancer five months, and the average overall survival of 15 months.
Okamoto believes that these positive results when compared with the results of testing two-way platinum chemotherapy treatment, levels of response ranged between 17 and 33%, and the survival periods ranged from the worsening of cancer cases between three and five months, and the average total stay of seven to 14 months.
The researcher, this experimental treatment promising alternative, but needs more tests of the random testing during the two-way.
Source: aljazeera
Copyright 2009
This Informations Collected And Translated From Arabic Language By Mesothelioma Guide
Two studies give hope for some Mesothelioma lung cancer patients
A new drug for cancer called “Iereesa” impressive results in the treatment of lung cancer, which is considered the most deadly types of cancer in most countries of the world.
However, the limits of the “Iereesa” that the rate of only 15% of the patients to enable them benefit from the research after the lack of response from the majority of patients to the drug.
The teams from Harvard Medical School in Boston, and other hospitals, there is a change in the gene controlling the protein growth factor called the future of skin cancer in patients with non-small cell lung, so the cells are not able to control it might be fatal in the end.
The non-small lung cancer cell responsible for the deaths of 85% of lung cancers, and caused the deaths of more than 157 people in the United States last year.
The researchers said that the Americans are genetically rapid examination may help to identify any of the injured lung cancer to enable them to benefit from Iereesa.
And Dr. William Sellers of Dana-Farber Cancer Institute at Harvard University who participated in the study, said that “Iereesa” failed to obtain a license from the U.S. Food and Drug Administration because the positive results did not appear only on a small percentage of patients.
He also expressed fear that pharmaceutical companies use the study to pressure in order to obtain a license to and delivery of cancer drugs to patients in need.
Source: Reuters
Copyright 2009
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Indoor air pollution increase the risk of Mesothelioma lung cancer
The results of a study involving several scientific centers that, despite the lack of prevalence of lung cancer in developing countries, the use of solid fuels for cooking and heating in homes contributes to the increased risk of developing the disease.
In the American Journal of Epidemiology reviewed Jolanta Lissowska a researcher at the Cancer Center and the Institute or. Skludovesca guilty of tumors in Warsaw and his colleagues, the results of a large study analyzed the role of combustion fumes from the cooking and heating in the house in the incidence of lung cancer.
The researchers said that the use of solid fuel for cooking or heating increased the risk of cancer by 22% compared with never using solid fuel for cooking or heating.
Shows that those from solid fuels used throughout their lives and faced the highest risk by 80% and the incidence of lung cancer, compared with an increase of 16% among those who have turned to modern fuels.
Said Jolanta Lissowska The high levels of indoor air pollution - which is currently taking place in the industrialized countries - may contribute to the risk of lung cancer, “This, however, small compared with the impact of tobacco smoking.”
“The International Agency for Cancer Research has just completed a study of lung cancer in several places in India, aiming to replicate the results of our study. There are other projects are under way in coordination with the International Agency for Cancer Research.”
Source: Reuters
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Tomatoes protect against Mesothelioma lung cancer
Tomatoes protect against Mesothelioma lung cancer
A new scientific study revealed that the tomato has the ability to preemptively against lung cancer, after previous studies had shown that its role in protecting men from prostate cancer.
The new study by a team of researchers in Finland found that it is apples and tomatoes may be the most beneficial fruits and vegetables for health.
The scientists said the food for 27 thousand men who are smokers aged between 50 and 69 years over 15 years, and found that fruits and vegetables, fresh fruit, especially the red tomato-rich vehicles “Korotenwid” and “Aecupen” chemicals known to be effective antioxidants reduce the risk of lung cancer.
The scientists in their study, published in the American Journal of Epidemiology that the most important risk factor for this disease is cigarette smoking, so it is the abandonment of the harmful habit with a healthy intake of food is a useful way to better prevention.
The earlier research had shown that eating apples and tomatoes strengthens the lungs, and that the treatment of fresh fruits and vegetables can reduce the risk of asthma and chronic lung diseases.
Source: Kods Press
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Japanese meal for the prevention of Mesothelioma lung cancer
Japanese scientists say that eating too much of the famous Japanese dish called Sushi (Sushi), which depends on fish reduces the risk of smokers with lung cancer, although the Japanese, who consume the same amount consumed by Americans and British cigarettes, however, lung cancer rates have much less.
It is believed Professor Toshiro Adji Takazaki of the Center for Cancer in the Japanese city of Nagoya that the reason for the low incidence of lung cancer among smokers due to the Japanese for the Japanese love this kind of food. The infection rates of the equivalent of Japanese smokers with lung cancer, infection rates of two-thirds of British smokers, the same disease, although Tkavihma in the number of cigarettes smoked.
The Professor Toshiro Takazaki and his colleagues conducted a study of food items favored by the four thousand Japanese sound from any illness and food items favored by the people infected with lung cancer, with a view to identifying the relationship between food and the incidence of this disease.
The study found lower rates of lung cancer in people who eat meals in large quantities of fresh fish or sushi.
Lung cancer is one of the most dangerous types of cancer and lead to death in most cases, the prospects for survival does not exceed 10% of it, leading to the death of 80% of patients in the years from the date of injury.
And contribute to dealing with fresh fish, in particular in the prevention of infection of the type of lung cancer known as glioma Glandular. The emergence of low rates of malignant tumors in people who have dealt with the idea of sushi and fresh fish always.
Does not contribute to addressing the dried or salted fish in the prevention of these diseases, but other scientific studies in the view of his contribution to increasing the risk of lung cancer.
Scientists do not know the real reasons behind the contribution of fresh fish to reduce the incidence of lung cancer, but they suspect that the reason is the multi-fatty acid and unsaturated fat found in fish.
There were no previous studies have examined the relationship between eating fish, fresh and reduce the risk of lung cancer is inconclusive.
Tobacco use is the leading cause of lung cancer, the researchers estimated the number of victims who lose their lives to the disease one billion people in the twentieth century, atheist, and if there has been no change to the current smoking rates.
Source:aljazeera + Reuters
Copyright 2009
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Exhale for the diagnosis of lung cancer
A medical examination of the possibility of a simple test to breathe in some cases, the diagnosis of lung cancer in patients even in the early stages of the disease, which demonstrates the principle that the idea could lead to good results.
The breath test device, the size of a coin, detected three-quarters of people living with lung cancer who underwent the test of using this tool by U.S. researchers from the Cleveland Clinic in Ohio.
But it had too many false positives means that it refers to the existence of lung cancer in persons not infected with the disease.
However, the researchers said that such a test is possible in principle if someone developed a more accurate version of this device.
The research team said that the unique chemical signature of the breath of patients with lung cancer can be detected with moderate accuracy by sensor blur the focus on measuring the colors of certain elements.
Researchers know that tumor cells produce different compounds than normal cells and this should be the volatile organic compounds, especially in the monitoring of lung cancer, because people exhale air these cells.
Tests show - using large machines called for comprehensive measures wavelengths - that such a test should be possible, but very costly in line with the average patient.
The team worked with the company, “Kimsinceng of Campaign” at Illinois to develop a simple test that can be placed in a portable.
So far, more accurate detection of cancer in dogs is as 2006, researchers found that they can be trained to smell cancer in the breath of patients 99% accuracy.
A type of X-ray, “X-ray”, called X-class computer screw or “CT”, revealed that lung cancer early, the seeds of other non-cancerous, but expensive.
And allow early diagnosis of lung cancer, where treatment is still possible, saving hundreds of thousands of lives each year the United States alone since it is one of the most common form of malignant cancer and also kills the most people, in part because it is not usually detected until it has spread.
In the past year was diagnosed with lung cancer in more than 174 thousand Americans died, including more than 160 people. The die of the disease killed 1.3 million people annually around the world.
Source: Reuters
Copyright 2009
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Genetic testing will help in the detection of lung cancer
U.S. researchers have discovered a test may be useful in predicting who suffer lung cancer killer.
The researchers said the test, which reveals the lethal genes in the lungs of people from the groups most vulnerable to lung cancer may help in identifying those who may already be infected the disease.
But researchers also said that the test is not accurate, so far, enough to be widely used, but it might replace the X-ray risky and costly.
The head of the Action Team program manager Stephen Plinski lung cancer at the Institute of Lovelace Respiratory Research in Albuquerque, New Mexico, “Unless we examine a number of times the lung X-ray to detect any tumors, there is emerging, we have no means to test those most at risk of lung cancer to be diagnosed with the disease at a later stage. ”
He added in a statement: “When proficiency testing and to ensure the accuracy of such tests had been successful in detecting lung cancer early enough for treatment.”
The Plinski and the number of his colleagues in the March 15 issue of the journal Cancer Research, which conducted the test succeeded in detecting 65% of the cases that have been symptoms of lung cancer in 18 months but at the same time and the wrong type 35% of the volunteers not infected with cancer patients as the .
The test examines the DNA in lung cells in sputum, and it is known that some genes are discouraged in the lung cancer.
It remains alive for more than five years, only 15% of patients with lung cancer and is due in part to the fact that the disease do not show many of the symptoms early and most people are not only diagnosed with the cancer has spread in the body.
Plinski said, “because most people are diagnosed with the disease at a time when the cancer is at an advanced stage, the surgical intervention and treatment of chemotherapy and radiation does not benefit them, therefore, the survival rate after diagnosis is only 13 months.”
Source: Reuters
Experts stress the importance of early detection of lung cancer
Medical experts have revealed that lung cancer kills a person every minute in Asia, and that in most cases, the disease has been detected at a late stage is not feasible with the treatment.
The experts urged the authorities to consider ways to detect lung cancer early, including the increased use of surface survey of television and computer means more effective in detecting the disease X-ray.
Said Tony Mok, professor in the Department of Clinical Oncology at the Prince of Wales Hospital in Hong Kong, said that 60 to 70% of cases of lung cancer that are diagnosed at a late stage, which means that most of that is in a state can not be recovered.
States that lung cancer is the leading cause of cancer deaths among men and women, and caused each year in the deaths of more than 570 people in Asia annually.
Tobacco use is the leading cause of lung cancer, is expected to increase the number of people each year the disease kills them in Asia, in the light of the continued increase in the number of smokers.
Source: French
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This Informations Collected And Translated From Arabic Language By Mesothelioma Guide
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