A group of scientists in Australia have discovered a new potential treatment for mesothelioma cancer victims with the application of two treatments normally reserved for skin cancer patients.During several tests conducted on laboratory mice with advanced mesothelioma tumors, a skin cancer cream known as Imiquimod was combined with an anti-cancer drug, antiCD40. The two were applied to the mesothelioma mice and, according to researchers, 50 percent of the mice receiving the treatment therapy went into remission following treatment.

The study, conducted by researchers from the Sir Charles Gairdner Hospital in Australia, is considered “breakthrough” according to a PerthNow news article. Additionally, scientists feel that this potentially new mesothelioma treatment may be more readily available than other treatments being researched and tested, as one of the drugs is “already commercially available and the other is currently being tested in clinical trials,” according to lead researchers of the study.

Mesothelioma Defined

Mesothelioma is a cancer that affects thousands of individuals worldwide. It has largely been classified as a relatively rare condition, although many physicians and scientists predict a large increase of victims in the near future because of the dormant nature of the cancer. Mesothelioma cancer is caused by exposure to varied levels of asbestos fibers and dust.

During the early part of the 20th century asbestos, which derives from vermiculite, was mined and used in a plethora of products and much more heavily within the construction industry leading to the diagnosis of many construction-related workers.

Mesothelioma cancer commonly remains dormant for 10 to 30 years until symptoms begin to appear, at which point, treatment is almost non-existent.

Patients of mesothelioma cancer are advised to speak with a medical professional immediately and those who suspect they may suffer from asbestos-related conditions can also suggested to contact a medical professional and experienced mesothelioma attorney for additional information.

Diagnosing Mesothelioma

Mesothelioma is a growing condition in not only America, but around the world. A mesothelioma diagnosis is often a grim and bitter situation for not only a victim, but for family members and friends.

Once an individual has been informed of their condition, they will need to take immediate steps to ensure the best quality of care is received. By determining this, an individual increases their chances of receiving monetary compensation for their disease through the development of a mesothelioma lawsuit.

Such compensation can assist a victim with paying for costly medical treatments including chemotherapy treatments, which can range in the thousands. Speaking with a knowledgeable mesothelioma lawyer can provide insightful information as to a potential lawsuit.

DefinitionThe most thorough definition of mesothelioma describes it as a rare cancer caused by asbestos fibers that have been lodged in the mesothelium for many years. The mesothelium is the membrane that encases organs such as the lung, the heart and those of the abdomen. Although it takes many years, these fibers can cause cancer cells to grow in the membrane tissue surrounding the fibers.

Mesothelioma most often develops in the membrane surrounding the lung, and results from inhaled asbestos fibers. This mesothelial membrane is called the pleura. Because lung tissue is so soft and porous, the motion of breathing massages the fibers through the lung tissue to the membrane. The consistency of the membrane is such that the fibers penetrate the pleura and remain trapped there.

Occasionally, fibers that are swallowed follow a similar path through the stomach wall where they become lodged in the lining around the stomach, called the peritoneum. With less frequency, fibers can pass through to the lining around the heart, called the pericardium. Mesothelioma can grow in any of these membranes.

Symptoms

Pleural mesothelioma symptoms can include thickening of the pleura, pleural effusion (fluid collecting in the pleural space), which in turn compresses the lung in that area reducing the amount of oxygen that can get into the blood. This causes shortness of breath along with some pain due to inflammation and, sometimes, infection. Persistent cough is common.

Symptoms of peritoneal mesothelioma might include stomach pain or swelling, bowel obstruction, foot swelling, nausea, weight loss, and pain.

Fever, night sweats, or anemia might also be symptoms of either form of mesothelioma. Diagnosis involves specific testing to differentiate it from other diseases, many of which have similar symptoms.

Diagnosis

There are a number of diagnostic tests that are used together with the results of a physical exam to make a diagnosis of mesothelioma. These tests differentiate between diseases and allow the doctor to rule out other diseases and cancers, identifying mesothelioma as the one that matches all of the diagnostic criteria. These include:

• X-rays - X-rays can reveal pleural effusion, pleural calcification, and scarring
• CT or CAT Scan (Computed Axial Tomography) - CT Scans identify tissue density and can identify pleural effusion, pleural thickening and calcification, but it can’t differentiate between mesothelioma and other disease.
• MRI (Magnetic Resonance Imaging) - An MRI is more sensitive than CT or X-ray, and is useful for more accurate identification of tissue changes during the course of treatment, and evaluating for surgery.
• PET Scan (Positron Emission Tomography) - PET Scans measure cellular activity. Cancer cells are more active than healthy cells, and this activity shows up in PET Scans.
• Biopsy - A biopsy involves taking a sample of the suspect tissue, either with a needle or through a small incision, and sent to the lab for analysis.
• PFT (Pulmonary Function Testing) - PFT involves a set of breathing tests to measure your lung volume, elasticity, airflow, and gas exchange into your bloodstream. These measurements reveal whether areas of your lung have a reduced volume or are not exchanging gas (i.e., from pleural effusion and resulting atelectasis, aka collapsed lung,) restrictive lung disease, or reduced airflow from obstructive lung disease.
• CBC (Complete Blood Count) - CBC shows the number of red and white blood cells and platelets, the amount of hemoglobin, and the percent of blood that is red blood cells. It also tests other common blood factors that indicate health and illness.
• Bronchoscopy - A bronchoscope is inserted into the patient’s lungs through the throat that allows the doctor to view the trachea and upper airways. The scope has the ability to take a tissue sample that can be examined under a microscope, in the same was as tissue collected from a biopsy.
• Cytology - A pathologist microscopically examines cells drawn from fluid near the site of the suspected disease.

The U.S. Department of Labor gives links to OSHA’s standards and guidelines for evaluating exposure to asbestos. These links include medical questionnaires, X-ray interpretation standards, medical surveillance for asbestos and more.