A new drug for the most common types of Mesothelioma lung cancers
The scientists tested a new drug to determine the extent of its ability to initial treatment for the most common types of lung cancers.
And know the name of the new drug Tarceva, which is produced by Roche and Genntek Osei, was finally adopted in the United States.
June British scientists at the Center for Research on Cancer and the University of London University Kdig to try the drug on 664 patients with advanced lung cancer cells, a type of non-small can be treated by conventional means.
Researchers say the President, Dr. Siu Meng Li conventional chemotherapy did not help very much in the treatment of advanced lung cancer cells that neoplasms quickly become resistant to treatment, while chemotherapy does not distinguish adequately between the cells Almtsrtunp and other sound effects in addition to the side difficult for patients with lung cancer that Ikavhoha successfully.
Tarceva is one of the new cancer drugs known as medicines, “smart” as the pill only in the day that used to impede the movement of the patient molecule known as “the future of the human growth factor”, which convey the orders to the cells to grow and make it fall.
The scientists in addition to monitoring the evolution of the situation analysis of patient tumors and determine the quality and the proportion of the molecule in the body to determine the extent of the patient’s response to the drug in question.
Meng Li says, “The testing of such a large-scale will play a decisive role in the evaluation of the new smart cancer drugs and to have access to the most effective types and distribution to the clinics as soon as possible.”
States that lung cancer is the most common cancer in the world, affecting 900 thousand men and 330 thousand women in the world each year, according to the international body of research in the field of cancer.
The proportion of cases of lung cancer than non-small cell to 75% of all cases of lung cancer, and return to the diagnosis of the disease are often in the later stages.
The other hand, will test the drug in 100 health centers in Britain, where patients will be selected at random and given some of Tarceva, while giving others a similar bogus pills in addition to radiotherapy, if found necessary, as the scientists hope to complete those tests within a year from now.
Meng Li says, “If the drug proved successful, it will be an ideal treatment.”
Source: Reuters
Copyright 2009
This Informations Collected And Translated From Arabic Language By Mesothelioma Guide
The experience of chemotherapy for lung cancer show promising potential
Mazen Al Najjar
The experience of treatment using a Japanese real estate experienced chemotherapy for the treatment of various cancerous tumors, they were together a promising alternative to conventional treatment or standard of cases of advanced lung cancer, according to the American Cancer Research, published the outcome of the experiment patrolling “Clinical Cancer Research.”
The clinical trial was conducted in several centers, and in the second phase of the experiment involved 56 patients with advanced cases of lung cancer commonly.
The results of the experiment of using real estate and S-1 Irenotikan in terms of the level of response, and the continued aggravation of the lives of patients without cancer, and the total length of stay, similar or better results for the treatment of the standard chemotherapy regime Platini.
Platinum toxic treatment
Because they are single-track experience, with all the participants received the same experimental treatment, without addressing the treatment group compared to standard chemotherapy, the researchers could not directly compare the benefits of both methods of treatment.
However, they did not mention whether the experimental treatment side effects less severe than those caused usually the standard treatment. It seems that the patients and their doctors rejecting the toxicity of chemotherapy, the platinum standard, given the lack of usefulness in the life of patients, which reinforces the need for effective treatments, the least toxic effects.
The author of the study and professor of Oncology, Faculty of Medicine, University of Osaka created kinky Isamu Okamoto of Japan should conduct a remedial “dual track” for a direct comparison between the experimental treatment and to establish the standard treatment of any benefits in prolonging the survival of patients with the use of real estate and S-1 Irenotikan.
Three mechanisms of action
The drug S-1 has approved its use in Japan and Korea, which showed significant benefit in the treatment of cancer of the digestive system, but it is still under clinical trials in other countries, such as Europe and the United States.
This multi-faceted real estate available in the form of capsules, the three different mechanisms. Disintegrate in one to Vrurassel (5-FU), as soon as his body. The Alvrurassel chemotherapy drug often used to treat cancers of the colon and rectum, and others.
There is a second part of the drug S-1 will continue in the production of Vrurassel fixed, while the third is designed to address the effects of toxic Vrurassel, Kalgthian and vomiting.
Irenotikan The drug is injected intravenously, and was originally developed and tested in Japan, the United States was approved in 1994, and is often used to treat colon cancer. And is currently being used in Japan to treat lung cancer, but it is not used in such other countries.
Level of response and survival
Japanese researchers believe that the combination of real estate and S-1 provides Irenotikan impact of solidarity. When tested the drug S-1 as the first chemotherapy treatment for advanced lung cancer cases, the level of response was 22%, while continuing to stay at an average of 10.2 months.
For the completion of the study, enrolled in this trial patients with advanced lung cancer cases did not receive any treatment, in 14 treatment centers in Japan, where they received an average of five sessions of the experimental treatment. The level of response was 28%, and the average stay about the worsening of cancer five months, and the average overall survival of 15 months.
Okamoto believes that these positive results when compared with the results of testing two-way platinum chemotherapy treatment, levels of response ranged between 17 and 33%, and the survival periods ranged from the worsening of cancer cases between three and five months, and the average total stay of seven to 14 months.
The researcher, this experimental treatment promising alternative, but needs more tests of the random testing during the two-way.
Source: aljazeera
Copyright 2009
This Informations Collected And Translated From Arabic Language By Mesothelioma Guide
Two studies give hope for some Mesothelioma lung cancer patients
A new drug for cancer called “Iereesa” impressive results in the treatment of lung cancer, which is considered the most deadly types of cancer in most countries of the world.
However, the limits of the “Iereesa” that the rate of only 15% of the patients to enable them benefit from the research after the lack of response from the majority of patients to the drug.
The teams from Harvard Medical School in Boston, and other hospitals, there is a change in the gene controlling the protein growth factor called the future of skin cancer in patients with non-small cell lung, so the cells are not able to control it might be fatal in the end.
The non-small lung cancer cell responsible for the deaths of 85% of lung cancers, and caused the deaths of more than 157 people in the United States last year.
The researchers said that the Americans are genetically rapid examination may help to identify any of the injured lung cancer to enable them to benefit from Iereesa.
And Dr. William Sellers of Dana-Farber Cancer Institute at Harvard University who participated in the study, said that “Iereesa” failed to obtain a license from the U.S. Food and Drug Administration because the positive results did not appear only on a small percentage of patients.
He also expressed fear that pharmaceutical companies use the study to pressure in order to obtain a license to and delivery of cancer drugs to patients in need.
Source: Reuters
Copyright 2009
This Informations Collected And Translated From Arabic Language By Mesothelioma Guide
A new breath test reveals Mesothelioma lung cancer
A new breath test reveals Mesothelioma lung cancer
Researchers find that the breath test a sensor to detect small lung cancer with moderate accuracy.
The device, which contains 36 vehicles attached to a chemical spill on the disclosure of sensitive models for volatile organic constituents in the breath, and these points change color when exposed to certain chemicals.
The aim of the study, published in the medical journal Thorax to determine the feasibility of establishing a multi-color models that can accurately detect the disease.
The tests were carried out on 49 patients suffering from lung cancer and 73 patients with other types of disease, and non-malignant lung disease and 21 were subject to medical examinations.
And enable the model set by the researchers to identify 73% of the cancer, while the description is wrong 28% of the cases which do not contain malignant tumors as cancerous.
“The. Peter MAZZONI of the Cleveland Clinic, Ohio, that further work may clarify the nature of the distinct elements of breath, he added, “This will help to clean the sensor and a collection of breath to reach the maximum accuracy in the diagnosis of the test.”
Source: Reuters
Copyright 2009
This Informations Collected And Translated From Arabic Language By Mesothelioma Guide
Disclosure of important steps for the treatment of lung cancer
The number of people living with lung cancer, up 1.3 million people annually
Revealed the first European Conference of lung tumors in Geneva on new research in the field of diagnosis and treatment of lung cancer at an early date and the prospects for the prevention of the emergence of tumors after treatment.
The inauguration of this conference, which took place in the period between 24 and 27 April
A database for the exchange of information on the latest developments in research and treatment of this pernicious disease.
Three genes
The Italian researchers reported in a scientific paper to the conference, that the genetic analysis could help in identifying patients at risk of a major setback after the surgery, the removal of tumors of the lung.
The president of the research, Professor Guido Natoli from Italy, “The track mark of three specific genes that could help in the tumors of lung specialists to choose the best treatment after surgery, to ensure that the spread of cancer cells again.”
Strengthen the immune
On the other hand, discussed the conference - which is the first fruit of cooperation between the European Society for Medical Oncology and the International Association for the study of lung cancer - research on the impact of gene therapy using anti-cancer cells.
Said Professor Johan Vannsteinkest from Belgium, “The results of this method to relieve the patient’s exposure to any side effects when used self chemotherapy after removal of tumors of the lung.”
This method relies on the patient during the injection of certain doses of a substance specific MAGE-A3 ASCI Vannsteinkest asserts that it was working to strengthen the immune system cells in the lung.
Database
During this conference inaugurated the database could be open to the Internet, including information on the results and steps to treat 12244 patients, specialists will be exposed through the development of specific types of treatment, and how the patient’s response to them and under what circumstances.
According to the statistics of the World Health Organization, the number of people living with lung cancer each year up to 1.3 million people 90% of them are smokers.
The proportion of deaths due to lung cancer, approximately 12.5% of deaths annually in the world, which is equivalent to 11 million people.
Source: aljazeera
Copyright 2009
This Informations Collected And Translated From Arabic Language By Mesothelioma Guide
Green tea protects Asians from cancer
Reuters
Despite the fact that smoking is known to cause heart disease and lung cancer, the rates of these diseases is still low despite the Asian countries where the prevalence of smoking, the researchers say that there is more evidence of the existence of the relationship between green tea and the lower those rates.
The researchers at Yale University in the Journal of the American College of Surgeons, in detail the evidence on the link between green tea to better heart health and a lower risk of cancer.
Said Bauer E. Sumpio and his colleagues at the Yale University School of Medicine in New Haven Bikunitict, the research said that the high concentration of antioxidants found the tea may have many health benefits.
And Antioxidants help to quell the particles known as molecules of the extra electron, which, if increased could lead to damage to the body’s cells and thus to diseases, and these particles are produced naturally in the body as it can reach the body from external sources such as smoking tobacco.
In Japan, China and other Asian countries, the drinking green tea is a social custom which is less processed and richer in catechins than black tea commonly consumed in the West.
Contradiction
According to Sumpio and his colleagues that the practice may explain the so-called Asian paradox. The researchers point out that the contradiction is reflected in the consideration of the figures relating to health, in different regions of the world.
For example, 348 people die every hundred thousand American men because of coronary heart disease each year, while the total number 186, although Japan’s higher rate of smoking.
And heart disease develops when the coronary artery narrowing and become the walls of the arteries feeding the heart of more solid because of the accumulation of cholesterol.
The team said that the researchers said laboratory tests found that the antioxidants green tea, may help in the prevention of these diseases through their effects on LDL cholesterol.
And perhaps help in antioxidants, also to the maintenance of the walls of the arteries in good condition and prevent blood cells from sticking together and forming clots.
Laboratory studies have shown that the materials antioxidants present in green tea may prevent tumor formation or growth in a number of forms, the researchers say it may help to explain why the death rate from lung cancer in Korea is unexpectedly low.
Copyright 2009
This Informations Collected And Translated From Arabic Language By Mesothelioma Guide
Construction Journal Reports Mesothelioma Deaths To Peak By 2015??
Working in the construction industry can be a dangerous job, as the number of fatalities and injuries continue to rise and are accounting for one-third of all employment fatalities, according to the most recent 2007/2008 Health and Safety Executive’s (HSE) statistics. However, one of the most dangerous and hidden killers of construction industry employees may actually be the development of mesothelioma cancer, according to an October 2008 issue of Contract Journal.
The journal reported that of the several reasons construction workers die on the job include the following:
* falls from height
* moving or falling objects
* moving machinery
* slips and trips
* asbestos exposure
Of the mesothelioma and asbestosis deaths, the HSE reports that, “in 2006 there were 111 deaths from asbestosis and 2,056 from mesothelioma and the HSE expects deaths from mesothelioma to peak at some point between current levels and 2,450 at some time before 2015.” An additional report from the HSE found that in the United Kingdom alone, there were approximately 4,000 deaths from mesothelioma each year, with a large portion of this number likely deriving from employees within the construction industry.
Mesothelioma cancer is caused by exposure to asbestos fibers and asbestos dust. Asbestos, which was derived from a mineral known as vermiculite, was heavily mined and valued within the construction industry for its fire-retardant qualities as well as its inexpensive costs for mass production. The Occupation and Safety Health Administration (OSHA) describes asbestos in the construction industry as a “a group of naturally occurring, fibrous minerals with high tensile strength, flexibility, and resistance to heat, chemicals and electricity.” It was used, according to OSHA, as part of the following products within the construction industry:
* sprayed-on fireproofing
* pipe insulation
* drywall joint compounds
* roofing felts and shingles
* ceiling tiles
* fire-resistant drywall
* acoustical products
* cement pipe and sheet
* floor tiles
Asbestos and Construction
While OSHA has developed standards for the construction industry as per the Occupational Standards Safety Act of 1970, the industry remains unregulated to a degree. For example, a recent report from the Georgia Environmental Protection Division (EPD) found that a standard U.S. Environmental Protection Agency (EPA) check in Florida revealed thousands of falsified documents for individuals employed to remove asbestos. It is a legal requirement that individuals who are in charge of asbestos removal receive authentic certification for their employment. However, thousands of documents had been forged with false or illegally obtained social security numbers.
Developing Mesothelioma Litigation
Individuals who have suffered from the debilitating condition of mesothelioma cancer could potentially qualify for a return of monetary compensation with the development of a mesothelioma lawsuit. If costly medical bills become too much for an individual who is suffering from this rare and painful condition, they may be able to discuss litigation with a knowledgeable mesothelioma attorney.
About the Author
Peter Kent is the best-selling author of 50 books and hundreds of articles for magazines and newspapers. He manages Legalview.com, a website hosting a variety of information on legal issues, including Mesothelioma.
Working Towards a Mesothelioma Cure
An understanding of mesothelioma symptoms can help in the process of mesothelioma cure. Some common symptoms of mesothelioma are difficulty in breathing, chest pain, and chronic cough. However, many times this disease lies in asymptomatic in the body, which makes mesothelioma cure an impossible task.
Once detected, the chances of survival of an average mesothelioma patient are very bleak. The options for Mesothelioma cure depend upon the different stages of the disease. In the first stage the treatments options depends on factors such as patient’s age, general health, organ affected and the size of tumor.
Surgery comes in two forms; aggressive surgery and palliative procedures. Aggressive surgery is a very difficult procedure and consists of removing large chunks of cancerous cells in an attempt to gain long term control over the cancer. Palliative procedures just attempts to lessen the symptoms for the patient.
What Is The Prognosis For a mesothelioma cure?
Mesothelioma cure in these stages involves draining of the fluid to reduce discomfort. This process of treatment is known as Thorancentesis or Paracentesis. After this, the doctors use Surgery followed by radiation and chemotherapy. Treatment and efforts for mesothelioma cure can suffer a severe jolt if the disease strikes back. In that case, the treatment depends on the location of recurrence, and the patient’s medical history.
This is highly dependent on how early and how aggressively the cancer is treated. If pericardial mesothelioma is treated when it has fully developed and matured then the chances of a patient’s survival is very small. The prognosis could be only a couple of months. Research into cures of pericardial mesothelioma and all other forms of mesothelioma is being done in numerous research labs all over the USA. Many pharmaceutical companies are also working hard to research new drugs for chemotherapy. So far, research has been mostly unsuccessful.
About the Author
To learn more about asbestos and asbestos related disease visit Asbestos Related Disease as well as Mesothelioma Cure
Asbestosis Causing Danger Zones at Home and at Work
Men are more likely to suffer from asbestosis and mesothelioma than women - likely due to the industrial nature of occupations in the past, which required daily heavy doses of asbestos long before effective regulations for working with asbestos were put into place. Individuals who have worked with asbestos and then were diagnosed with mesothelioma are typically over 50 years old, and often, diagnosis does not occur until many are in their 70’s.
Sadly, mesothelioma has even been detected in persons with a short history of asbestos exposure. The fine slivered hairs that are the trademark of asbestos are capable of scarring the lungs or chest of any man, woman or child who is exposed to airborne asbestos. Because of its clingy nature, asbestos was often brought into the home by asbestos industrial workers, and unsuspectedly worked its way into the lungs of family members. Housewives and homemakers were over 6% of the mesothelioma patients back in 1999 - indicating they were exposed to asbestos in the 1950’s, an era when there were more marriages and women were more likely to be doting on their husbands - including washing their asbestos-covered clothing.
Asbestos is used for walls and ceilings, sound-proofing, fire protection, insulation, vinyl floor tiles, and even insulation in common household appliances, such as toasters, irons, dishwashers, refrigerators and ovens. The homes and schools built prior to the 1970s were often filled with asbestos in the products that make up the walls, ceilings and insulation. Elementary school teachers were 2.4% of the cases in 1999, and managers, supervisors and administrators made up 10% of the cases.
The danger zones exist wherever asbestos is airborne. When asbestos-containing insulation around pipes becomes damaged, when walls are being removed for remodeling, or when an attic full of asbestos insulation is decaying, the entire building becomes a danger zone. Activating dry asbestos can be done merely by moving it or piercing it. Vacuuming asbestos severely multiplies its deadly affect. There are procedures referred to as “wet” handling of asbestos that lowers the risk of air-borne fibers. Trained asbestos handlers that are properly protected and experienced in asbestos removal and sealing should always be consulted. The risk of asbestos is neither visible nor immediate, but asbestosis and mesothelioma will likely be a part of your future if you have exposed yourself to a significant amount of the sharp flying fibers of asbestos.
Asbestosis and mesothelioma can clearly be avoided by not exposing yourself to airborne asbestos. Changing occupations or moving into a new house are not always viable options, however wearing proper protection and sealing any potential asbestos sources can keep you out of the danger zone. Read the materials listing on products you buy, and avoid buying from countries that ignore the risks of asbestos. Being aware of the dangers of asbestos and the potential of asbestosis and mesothelioma is the first step to prevention. Twenty years from now you’ll look back on today in good health, and not while suffering from the incurable diseases of asbestosis or mesothelioma.
About the Author
Asbestosis-Mesothelioma website provides Asbestosis, Mesothelioma and asbestos treatments news, care tips and many other useful information.
Mesothelioma New Cures on the Horizon for Asbestos Causing Cancer
Killing a tumor isn’t easy, and mesothelioma does not regress like other cancers, even after lung surgery. Just as a mix of the right individual talents can produce a powerful team, so can a mix of the right medications and treatment produce a powerful solution. Elementary science best demonstrates this with baking soda and vinegar. Each product has their unique properties that serve product-specific purposes, but when mixed together they can produce a volcanic effect. Finding the synergistic effect from combination drugs and therapies that can debilitate or conquer asbestos related diseases is the goal of mesothelioma and asbestosis clinical trials.
A 2007 medical study added on three months to the lives of mesothelioma patients who participated in clinical trials that used the vitamin supplements of B12 and folic acid along with Emetrexed and Cisplatin, when compared to mesothelioma patients that received Cisplatin without any supplements. Three months may not seem long to a person embraced in the rush of life, but it is a gift of life to the cancer sufferer facing imminent death.
Doxorubicin, a cancer drug for asbestos disease that’s been around for a while, is now being combined with Onconase. Doxorubicin damages the cancer cells, but the cancer cells can heal. Onconase is a drug that goes in and blocks the healing process. A similar clinical study is being done with Pemetrexed disodium, a drug classically prescribed for mesothelioma, combined with Gemcitabine or Carboplantin to determine the better combination. This would compare the results of two powerful drugs that block cancer cell growth versus a combination of one of those drugs with a drug that damages cancer cells.
Mesothelioma and its close relative Asbestosis are expected to reach higher diagnosis rates in the future. Asbestos use has been regulated in many countries, but its wide-spread use still remains. Hundreds of clinical trials for these asbestos diseases exist that will provide help, and maybe even a cure, for the asbestos-induced sufferers of the future. There is a light at the end of the long dark tunnel of mesothelioma. With continued medical research and clinical trials, the light will become brighter and brighter - until hopefully, mesothelioma will be left behind to become a part of the distant past.
About the Author
Asbestosis-Mesothelioma website provides Asbestosis, Mesothelioma and asbestos treatments news, care tips and many other useful information.
-
Translation :
Translator
